Study: No Difference in Ischemic Stroke Recovery When Endovascular Therapy Added to Clot-Busting Treatment


Joseph Broderick, MD, photo by UC Academic Health Center Communications Services.

Media contact:
(513) 558-4559

CINCINNATI—The use of devices or medication within the arteries to treat stroke-causing blood clots at the site of blockage failed to improve stroke outcomes compared with the current standard treatment of intravenous (IV) clot-busting medication alone, new research led by a University of Cincinnati (UC)  neurologist shows.

The study, being published online today (Thursday, Feb. 7), by the New England Journal of Medicine, was authored by Joseph Broderick, MD, Albert Barnes Voorheis Chair of Neurology and Rehabilitation Medicine at UC and research director of the UC Neuroscience Institute, one of four institutes of the UC College of Medicine and UC Health. Results were also being presented today at the American Heart Association/American Stroke Association’s International Stroke Conference 2013 in Honolulu.

“Our study highlights that improved reopening of arteries and delivery of blood flow to the brain was not a guarantee of improved clinical efficacy,” Dr. Broderick says. “It means we still have to answer the question of who benefits most from the new technology going inside the artery, because it takes a lot of time and effort and is more expensive.”

Patients studied for this research were part of the Interventional Management of Stroke III (IMS III) trial, begun in 2006 and funded by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH). With 656 adult stroke patients at 58 centers in the United States, Canada, Australia and Europe, it was the largest trial to date of an endovascular intervention for acute ischemic stroke (treatment delivered within the brain artery at the site of the clot), NINDS officials said. (Ischemic strokes occur as a result of an obstruction to the blood flow, typically a clot.)

Learn more >>

This entry was posted in Press Releases and tagged , , , , , , , . Bookmark the permalink. Both comments and trackbacks are currently closed.
  • Print This Page
  • Make an Appointment: Schedule Now
  • Sign up for our newsletter!
  • UCNI Weekly Blog
  • Hope Stories

    • Lynne’s Story

      Lynne's StorySemiretired and working part-time at a restaurant, Lynne knew something was amiss when she looked at the cash register and then struggled to make her hands produce the correct amount of change. Could she have suffered a stroke? Lynne pushed the...
    • Richard’s Story: Ruptured Aneurysms

      Richard's Story: Ruptured Aneurysms Almost three years ago, Richard “Dick” Watson, MD, found himself in an unfamiliar position for a doctor: lying on the operating table instead of standing over it. He didn’t know it at the time, but it was the beginning of...
    • Christine’s Story: Stroke

      Christine's Story: StrokeThere was a sliver of a chance, maybe, and most likely the emergency room doctor thought there was no chance at all. Christine had arrived at the community hospital comatose, brought by her parents, who had come home after working...
    • Amy’s Story: A Battle With MS

      Amy's Story: A Battle With MSIn retrospect, multiple sclerosis had probably been stalking Amy for a long time. She had suffered from chronic headaches in high school, and her seasonal allergies had been over the top. Then, in her mid-30s, the busy wife and mother...
    • Amber’s Story: Ruptured Aneurysm

      Amber's Story: Ruptured Aneurysm The only visible sign of Amber Gray’s ordeal is the long slender scar that runs along her forearm. It is the area where a surgeon carefully removed her radial artery, which was needed to bypass a damaged artery in her...
    • Zettie’s Story: Aphasia

      Zettie's Story: Aphasia In November of 2004, Zettie Williams confronted what neurologists consider one of the most feared consequences of stroke. When a therapist showed her a photograph of her son, she knew she was looking at her son, but she couldn’t say...
    • Renee’s Story: Stroke

      Renee's Story: Stroke When 33-year-old high energy mother Renee Young became ill with the flu in November 2007, the last thing she expected was she was about to suffer a stroke. But that was exactly what happened. As she tried to swallow medication...
    • Blake’s Story: Medulloblastoma

      Blake's Story: Medulloblastoma Blake knew he was in the right hands the moment he saw the surgeon’s wrists. Dr. John M. Tew, Blake’s neurosurgeon, was wearing one of Lance Armstrong’s yellow LiveStrong cancer bracelets. So was Blake. Dr. Tew, who was also sporting...
    • Sunny’s Story: A New MS Family

      Sunny's Story: A New MS Family As Sunny knows, one does not defeat multiple sclerosis. The disease is here today, and it is still here tomorrow. But with help from skilled,...
    • Mary Ann’s Story: Cervical Dystonia

      Mary Ann’s Story: Cervical Dystonia Mary Ann, a registered nurse, was the first to notice that her head was tilting ever so slightly to the left. She was able to ignore it for a while, but over time the tilt became more obvious and disfiguring....